i have iphone 4G, with version 4.3.3 so i upgrade it and after it will not except my simcard
It is a sign that your iPhone was jailbroken or hacked.
Otherwise get a new sim from your carrier.
Try restoring device in itunes.
If this does not resolve your issue, get a new sim card from your carrier.
http://support.apple.com/kb/HT2309 <---Sim swap
if i change sim than will complate or my phone is lock ?
You may need to connect the device to itunes after swapping the sim.
If the sim was faulty you have to change it. If it was not jailbroken why do you ask that question?
Officially unlocked iPhone do not lock again through update or sim change.
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