Generally, it is a YES.
Some cars have really integrated technology on bluetooth. Which that just meant it would automatically catch the calls and music to project it through the speakers. (altenatively that works with iPod Touch and iPhone to the capability of Bluetooth)
Unfortunately, some cars don't. The only way to fix that if you're lucky enough, you'd get an AUX plug built-in of your car, or a USB plug. (I wouldn't reconmmend using USB because it charges your device automatically and that's gonna shorten your device's battery life)
If you are still missing the gadgets above, you'd probably want to contact your car's support office and ask them about that, or go to the tuning shop closest to you and ask those guys (they are technically experts).
Hope this helped, thanks.