Ipad mini's side of screen unresponsive

My ipad mini have erratic bottom responsiveness when it lands onthe side of the screen, even typing it produces unresposive to hyper mode producing inaccurate text or tap a letter multiple times. Other bottons thatwontwork,I just change orientation of the ipad and hit the botton again.

Ipad minis every bit of an ipad2 except the ipad mini was added a program that changedtheflip of pages when reading e books, this might be the culprit onthe erratic responsiveness of the ipad mini, oh thereis also the hyper mode that bottons clicks on their own, please help.