You are likely to to find this problematic. However this Apple Tech Note does suggest it should be possible and gives you some information:
You will require iSync and, if you have not done so, you may need to download the iSync Palm Conduit (if you have iSync 2 or later you won't need it).
How well this is likely to work on Leopard (which your signature says you have) I can't say - the document was written with 10.3 in mind. You will probably realise that it won't work with anything higher than Snow Leopard (the Palm Desktop does run on that and will sync with a Palm device, but I don't know whether iSync is any use on it) - Lion and above cannot run the Palm Desktop and iSync will not talk to the Palm without the conduit (which won't run either).