10.8.3 uncontrolled memory hog and slowdown
I updated to 10.8.3 the machine was unusable from the start. Istat menus showed that system apps were consuming memory in increasing amounts even with no apps running nor any user input. The machine was very slow and virtually unresponsive to mouse/keyboard input.
I "cured" the problems by reverting to 10.8.2 which is where I intend to stay for as long as possible.
Mac Pro, OS X Mountain Lion (10.8.3), 24GB RAM : SSD for booting and apps