The permissions are totally wrong. It looks like someone has intentionally changed them.
First, since I don't know what other damage has been done, you should at the very least back up all data and then run Repair Permissions in Disk Utility. That action may fix some (not all) other files with wrong permissions, but it wont fix this one.
If you have more than one user account, you must be logged in as an administrator to carry out these instructions.
Triple-click anywhere in the line below to select it:
sudo chown 202:202 /L*/P*/A*/*.audio.*.plist; sudo chmod -N $_
Copy the selected text to the Clipboard (command-C).
Launch the Terminal application in any of the following ways:
☞ Enter the first few letters of its name into a Spotlight search. Select it in the results (it should be at the top.)
☞ In the Finder, select Go ▹ Utilities from the menu bar, or press the key combination shift-command-U. The application is in the folder that opens.
☞ Open LaunchPad. Click Utilities, then Terminal in the icon grid.
Paste into the Terminal window (command-V). You'll be prompted for your login password, which won't be displayed when you type it. If you don’t have a login password, you’ll need to set one before you can run the command. You may get a one-time warning not to screw up. Confirm. You don't need to post the warning. If you see a message that your username "is not in the sudoers file," then you're not logged in as an administrator.
Quit Terminal and reboot.
