Macbook Pro (10.8.3) doing weird things!!!
Last week my Macbook Pro (10.8.3) started behaving very strange... applications would not open (sometimes they would after a restart), I was consistently getting "error code -50", mail was also doing strange things, sometimes after a reboot it would stay on Grey Screen with Apple and spinning wheel, I would then have to reboot in Safe Mode then reboot again... I have regular backups via Time Machine... any advice welcome
MacBook Pro, OS X Mountain Lion (10.8.3)