Try rebotting the machine
Also try:
Quit all iWork applications
navigate to the "Library" for the problem user account by selecting the menu item (in the Finder) "Go > Go To Folder..."
then enter "~/Library/Preferences/"
now locate the files:
file://localhost/Users/wayne/Library/Preferences/com.apple.iWork.Keynote.LSShare dFileList.plist
file://localhost/Users/wayne/Library/Preferences/com.apple.iWork.Keynote.LSShare dFileList.plist.lockfile
file://localhost/Users/wayne/Library/Preferences/com.apple.iWork.Keynote.plist
file://localhost/Users/wayne/Library/Preferences/com.apple.iWork.Keynote.plist.l ockfile
file://localhost/Users/wayne/Library/Preferences/com.apple.iWork.Numbers.LSShare dFileList.plist
file://localhost/Users/wayne/Library/Preferences/com.apple.iWork.Numbers.plist
file://localhost/Users/wayne/Library/Preferences/com.apple.iWork.Pages.LSSharedF ileList.plist
file://localhost/Users/wayne/Library/Preferences/com.apple.iWork.Pages.LSSharedF ileList.plist.lockfile
file://localhost/Users/wayne/Library/Preferences/com.apple.iWork.Pages.plist
file://localhost/Users/wayne/Library/Preferences/com.apple.iWork.Pages.plist.loc kfile
And move them to the desktop
now start Numbers again.
If it launches then trash all of the files listed above (not if you only want to deal with Numbers filter the above list to just files that are "...com.apple.iWork.Numbers..."