Hi, I had this issue too.
In IE10, when visiting the page http://www.apple.com/uk/itunes/download/, you should get a notification saying: "Only Secure content is displayed" (If you don't see it hit F5 to refresh the page).
Click on the "Show all content button"

and then click on the blue "Download Button" and hopefully the download notification should appear prompting you to Run or Save:
