Indesign cs4 takes over CPU, crashes

Consult with Adobe on their forums and with others there about your issue and a resolution.

We can only advise uninstalling and reinstalling,

If it's a problem with OS X, then run through these fixes

..Step by Step to fix your Mac

Backup your data regardless.

Most commonly used backup methods

Oh, check for compatibility with your OS X version here

http://roaringapps.com/apps:table