No clear explanation on multiple hard drive software configuration?

Can you boot from SSD?

Did you clean install OS and Applications on SSD or using Migration Assistant?

Most apps have a preference for their media library.

Alias and symbolic links work

you could relocate the home account.

60GB is small and cutting it short, even though you only used say 25GB

you willl need to use TRIM Enabler of course. 10% should be allocated to over provisioning also.

the free space should equal how much is written in the course of a month.

and be ready to erase and restore as needed, always have another drive with TRIM Enabler and have a disk image or restore image of the SSD handy.

Using Cloning as a Backup Strategy

http://www.bombich.com/software/updates/ccc-3.5.html

Create an OS X Lion Install disc

How to create an OS X Lion installation disc MacFixIt

Migration Assistant Update for Mac OS X Snow Leopard

http://www.apple.com/support/lion/installrecovery/

http://reviews.cnet.com/8301-13727_7-20080989-263/how-to-create-an-os-x-lion-ins tallation-disc

http://www.coolestguyplanettech.com/how-to-make-a-bootable-osx-10-8-mountain-lio n-disc-or-drive-from-the-downloaded-mountain-lion-app/

How to clone your system:

http://macperformanceguide.com/Mac-HowToClone-backup.html

http://macperformanceguide.com/Mac-HowToClone.html

http://www.macupdate.com/app/mac/7032/carbon-copy-cloner

http://www.macperformanceguide.com/blog/2012/20120711_2-MacPro-internal-clone-ba ckup.html

Before you clone, install TRIM Enabler!

And after you clone, run Disk Utility's REPAIR DISK on the SSD -- just to be on the safest side.

http://www.macupdate.com/app/mac/37852/trim-enabler

SSD Maintenance

http://support.apple.com/kb/HT4337

http://chris.pirillo.com/how-to-move-the-home-folder-in-os-x-and-why/

To successfully relocate your operating system, user accounts and data from one storage device to another, meet the following conditions:

• The destination storage device (SSD drive or hard drive) you are migrating to should be physically located in the same computer. Moving operating system files from one computer to another computer using software not specifically designed for that computer can cause issues due to software, hardware, and firmware version mismatches.
• Always back up your storage device with Time Machine or Disk Utility before you start.

one more voice on relocating Users to a different drive:

Japamac's Blog: Make room for Performance -- Moving the Home Folder

It is a good idea to create a new Admin User that gets left behind on the Boot drive, if you do not already have one there. This will allow you to log in and use the Boot Drive alone even if the Users drive is not available. (No points off for having multiple Admin accounts.)