Linc, thanks for the post, one step closer, but still no luck.
Completed all of your steps, the services -> reveal method worked great.
After deleting the entire file "com.apple.mail" re-opened mail. Saw the file get re-created.
Preferences now opened, but as soon as I clicked on accounts tab, Mail freezes again. (After opening Mail a second time, now continues to freeze on Mail -> Preferences)
Additionally went to System Preferences -> Mail, Contacts & Calendars, deleted out all of the mail accounts.
Still same problem, only one e-mail account now up and running (icloud) and still have mail freezing on preferences. Any other ideas?
Here are the lines that posted as soon as I opened Mail.
7/5/13 8:55:17.375 PM com.apple.security.XPCKeychainSandboxCheck: Can't get dir or base (likely out of memory) for LAST.FIRST.MIDDLE.XXXXXXXX
7/5/13 8:55:17.686 PM Mail: Keychain sandbox consume extension error: s=-1 p= Cannot allocate memory
(There are about 1000 of the above line)
7/5/13 9:01:02.021 PM sandboxd: () Mail(652) deny mach-lookup DictationInputMethod_1_Connection
7/5/13 9:01:02.000 PM kernel: Sandbox: sandboxd(656) deny mach-lookup com.apple.coresymbolicationd
7/5/13 9:01:02.148 PM Mail: *** -[IADomainCache init]: IA domains cache is out of date.
7/5/13 9:01:21.086 PM SubmitDiagInfo: Submitted hang report: file://localhost/Library/Logs/DiagnosticReports/Safari_2013-07-05-160706_Andres kys-iMac.hang
7/5/13 9:01:21.845 PM SubmitDiagInfo: Submitted hang report: file://localhost/Library/Logs/DiagnosticReports/Google%20Chrome_2013-07-05-1607 13_Andreskys-iMac.hang
7/5/13 9:01:23.833 PM SubmitDiagInfo: Submitted hang report: file://localhost/Library/Logs/DiagnosticReports/Mail_2013-07-05-193402_Andresky s-iMac.hang
(There are multiple occurances of many of the above lines)
These are the two lines that showed up immediatly after sellecting the preferences in Mail, causing the program to freeze
7/5/13 9:03:18.620 PM sandboxd: () Mail(652) deny mach-lookup DictationInputMethod_1_Connection
7/5/13 9:03:20.590 PM Mail: [<_LibSasl2SASLClient: 0x7f82236872e0> mechanism: PLAIN security layer: no] Failed to start the SASL connection
SASL(-1): generic failure:
The first of the two lines had a full report that I can attach.
Pretty sure that somehow the CAC issue is correlated, also ran a disk-utility and found a file that was corrupt com.apple.preferences.internet.....XXXX-XXXX-XXXX-XXXXXXXXXXXX.plist
The disk utility was able to repair it though.
Thanks for the help so far.