Another me too over here.
Had my 15" screen replaced because of a smudge of glowing pixels, tiny, but definitely a manufacturing defect. It marred an otherwise spectacular screen - the best I've ever seen; very bright, neutral (perhaps a slight crisp coolness) colour.
Felt like the absolute state of the art in display technology. But that glowing splodge just niggled and niggled...
Got caught up in work (gotta pay for this thing somehow) for a couple of months, though - I left it long enough that the Apple store peeps had to replace the screen rather than the machine, and it's kinda heartbreaking that though all my pixels work now, this screen just isn't as clear. Same resolution, but the screen has a noticeable tobacco-filtery warmth to it that gives it a strangely vintage look.
I know I'm nit picking, but it's a disappointment.
Playing with the calibration will help but at the cost of slight brightness, and I'm considering one of those calibrator dongle thingies to try and do a decent job, but it feels like a workaround compared to what I had.
Despite all of this, it's still the most advanced and beautifully engineered machine I've ever had the luck to own. Gotta keep things in perspective. It's just not as good as it was.