But an external hard drive with the same or greater capacity than the computer's internal drive. Partition and format it GUID and Mac OS Extended, Journaled, respectively. Begin a backup strategy starting with a backup of the drive as it is now. You can use Time Machine or any other backup utility of your choice.
Basic Backup
For some people Time Machine will be more than adequate. Time Machine is part of OS X. There are two components:
1. A Time Machine preferences panel as part of System Preferences;
2. A Time Machine application located in the Applications folder. It is
used to manage backups and to restore backups. Time Machine
requires a backup drive that is at least twice the capacity of the
drive being backed up.
Alternatively, get an external drive at least equal in size to the internal hard drive and make (and maintain) a bootable clone/backup. You can make a bootable clone using the Restore option of Disk Utility. You can also make and maintain clones with good backup software. My personal recommendations are (order is not significant):
1. Carbon Copy Cloner
2. Data Backup
3. Deja Vu
4. SuperDuper!
5. Synk Pro
6. Tri-Backup
Visit The XLab FAQs and read the FAQ on backup and restore. Also read How to Back Up and Restore Your Files. For help with using Time Machine visit Pondini's Time Machine FAQ for help with all things Time Machine.
Although you can buy a complete external drive system, you can also put one together if you are so inclined. It's relatively easy and only requires a Phillips head screwdriver (typically.) You can purchase hard drives separately. This gives you an opportunity to shop for the best prices on a hard drive of your choice. Reliable brands include Seagate, Hitachi, Western Digital, Toshiba, and Fujitsu. You can find reviews and benchmarks on many drives at Storage Review.
Enclosures for FireWire and USB are readily available. You can find only FireWire enclosures, only USB enclosures, and enclosures that feature multiple ports. I would stress getting enclosures that use the Oxford chipsets especially for Firewire drives (911, 921, 922, for example.) You can find enclosures at places such as;
1. Cool Drives
2. OWC
3. WiebeTech
4. Firewire Direct
5. California Drives
6. NewEgg
All you need do is remove a case cover, mount the hard drive in the enclosure and connect the cables, then re-attach the case cover. Usually the only tool required is a small or medium Phillips screwdriver.
At present there is no need for anti-malware software:
Helpful Links Regarding Malware Protection
An excellent link to read is Tom Reed's Mac Malware Guide.
Also, visit The XLab FAQs and read Detecting and avoiding malware and spyware.
See these Apple articles:
Mac OS X Snow Leopard and malware detection
OS X Lion- Protect your Mac from malware
OS X Mountain Lion- Protect your Mac from malware
About file quarantine in OS X
If you require anti-virus protection I recommend using ClamXav.