Anyone know about this? "The iTunes Lirbrary file cannot be saved. -54 error message

I lost a drive, but had a back-up, so I started with the new drive, formatted Mac Journaled, copied the songs and iTunes Library over and got everything working (I think). Now I'm getting this message and I'm not sure what to do: The iTunes Library file cannot be saved. Unknown error occurrec (-54). Anyone???

Thanks in advance.

Randy