If you know their current answers then follow steps 1 to 5 half-way down this page and you should get to a screen where you can change them : http://support.apple.com/kb/HT5312
If you can't remember their answers and you have a rescue email address (which is not the same thing as an alternate email address) set up on your account then those steps should give you a reset link.
If you don't have a rescue email address (you won't be able to add one until you can answer 2 of your questions) then you will need to contact iTunes Support / Apple to get the questions reset.
Contacting Apple about account security : http://support.apple.com/kb/HT5699
When they've been reset (and if you don't already have a rescue email address) you can then use the steps half-way down this page to add a rescue email address for potential future use : http://support.apple.com/kb/HT5312