Q: iTunes will not open on pc

Just downloaded the newest version of iTunes, now it will not open on my pc. I uninstalled it, then reinstalled. It worked for one device, now won't open again. When I connect any of my 11 apple products to the computer, iTunes won't open, nor will the devices be recognized. Ran malware and Ccleaner programs for viruses or spyware.  Nothing. Everything else on the computer is fine. What can I do...I have new iPads for my classroom to set up.