Q: How can I get a refund for my in-app accidental purchase?

I bought my 72-year-old Mother a new iPad 2 and she is loving it. I set up the account for her to purchase new games through the app store if she wanted, but she was not aware that the in-app purchases were real-life purchases, she thought it was fake money inside the game (now she knows). Is it possible to get a refund for this? I tried to do it through the 'report a problem' but it said it was not refundable and $99.99 is a very big mistake to make on her first day with the iPad.

Any help would be appreciated.