iTunes began to freeze after accessing Store

Yesterday when I tried out iTunes radio (choosing songs to make stations) it froze and I had to end the task from the Task Manager. It has done this four times today, including once while running in Safe Mode. It usually crashes after I have connected to the internet or try to access the Store. When I restart it, it has lost most of the song plays I racked up between freezes. Any idea why this might be happening, and/or how to fix it?