Brett, that won't help if iTunes cannot open.
Karla, try these steps:
1. Please triple-click on the block of text below to select all of it, then press CTRL+C to copy it.
cmd /k REG ADD "HKCU\Software\Apple Computer, Inc.\iTunes" /v LangID /t REG_SZ /d "1033"
2. Press the WinLogoKey+R to open the Run... dialog.
3. Paste the text into the box with CTRL+V and then press enter/return. Overwrite the value if prompted.
Alternatively, if you are confident using the registry editor, open it and locate the key HKEY_CURRENT_USER\Software\Apple Computer, Inc.\iTunes. It might be useful to know what value is shown there now for LangID since several users are reporting this problem. Change the value of LangID to 1033 to tell iTunes to use English (United States). Once iTunes is able to start you can change this if needed, or you could look up the desired hex Locale ID from this table.
I've just used this technique several times to flip iTunes between English (US) and English (UK). Although I'm in the UK I prefer the US labels of Movies and TV Shows as opposed to Films and TV Programmes. I'm guessing that there is currently a value in your registry (or none at all?) that doesn't match with any of the languages that iTunes is customized for, although why it cannot switch to English automatically is another matter.
I've not had this problem myself, but I'm assuming at this point that correcting the user setting is all that needs to be done. Just in case however the following would correct the global setting which would normally be used when setting up a new user or if the current user hasn't been configured for the application.
Command to copy & paste:
cmd /k REG ADD "HKLM\Software\Apple Computer, Inc.\iTunes" /v InstalledLangID /t REG_SZ /d "1033"
or locate the key HKEY_LOCAL_MACHINE\Software\Apple Computer, Inc.\iTunes and edit:InstalledLangID to the value 1033.
Please let me know how you get on.
tt2