OS X 10. 7 Lion / 10.8 Mountain Lion / 10.9 Mavericks
About “Other”:
http://support.apple.com/kb/HT6047
Go step by step and test.
1. Start up in Safe Mode.
http://support.apple.com/kb/PH11212
2. Empty Trash.
http://support.apple.com/kb/PH10677
3. Delete "Recovered Messages", if any.
Hold the option key down and click "Go" menu in the Finder menu bar.
Select "Library" from the dropdown.
Library > Mail > V2 > Mailboxes
Delete "Recovered Messages", if any.
Empty Trash. Restart.
4. Repair Disk
Steps 1 through 7
http://support.apple.com/kb/PH5836
5. Disk space / Time Machine ?/ Local Snapshots
Local backups
http://support.apple.com/kb/ht4878
6. Delete old iOS Devices Backup.
iTunes > Preferences > Devices
Highlight the old Backups , press “Delete Backup” and then “OK”.
http://support.apple.com/kb/HT4946?viewlocale=en_US&locale=en_US
7. Re-index Macintosh HD.
System Preferences > Spotlight > Privacy