Once all the pictures are in iPhoto library and I delete these from my Pictures folder in Mac, Is there a way to archive or backup iPhoto pictures?
Of course. Most Simple Back Up:
Drag the iPhoto Library from your Pictures Folder to another Disk. This will make a copy on that disk.
Slightly more complex: Use an app that will do incremental back ups. This is a very good way to work. The first time you run the back up the app will make a complete copy of the Library. Thereafter it will update the back up with the changes you have made. That makes subsequent back ups much faster. Many of these apps also have scheduling capabilities: So set it up and it will do the back up automatically.
Example of such apps: Chronosync- but there are many others. Search on MacUpdateor the App Store
If you want to just back up the pics: File -> Export... This User Tip
https://discussions.apple.com/docs/DOC-4921
has details of the options in the Export dialogue.
2. Is there any use of having multiple iPhoto libraries?
Only if you can find a reason. Bur remember that iPhoto can only open one library at a time and so multiples can be inconvenient.
Last time I imported photos from Pictures folder to iPhoto, it showed me "no space in iPhoto library". Is there any way to not experience this again?
Download iPhoto Library Managerand use its rebuild function. (In early versions of Library Manager it's the File -> Rebuild command. In later versions it's under the Library menu.)
This will create an entirely new library. It will then copy (or try to) your photos and all the associated metadata and versions to this new Library, and arrange it as close as it can to what you had in the damaged Library. It does this based on information it finds in the iPhoto sharing mechanism - but that means that things not shared won't be there, so no slideshows, books or calendars, for instance - but it should get all your events, albums and keywords, faces and places back.
Because this process creates an entirely new library and leaves your old one untouched, it is non-destructive, and if you're not happy with the results you can simply return to your old one.