Will my MacBook Mid 2009 support Ram from 2X2GB to 2X8GB?

Up to 4GB of 667MHz DDR2 SDRAM This your Limit according to apple specs

Mid-2009 MacBook Pro's support up to 8GB RAM (2X4GB), that is what mine is running. The memory type is PC3-8500 DDR3 1067MHz, see page 44 here: http://manuals.info.apple.com/MANUALS/1000/MA1128/en_US/MacBook_Pro_15inch_Mid20 09.pdf (The 13" is identical in memory.) These are 204 pin SODIMM modules.