Open a Finder window. From the Finder menu bar click Go > Go to Folder
Type or copy paste the following
Click Go then move the Cache.db file to the Trash.
Quit and relaunch Safari to test.
If that didn't help, try troubleshooting extensions and third party plug-ins.
From the Safari menu bar click Safari > Preferences then select the Extensions tab. Turn that OFF, quit and relaunch Safari to test.
If that helped, turn one extension on then quit and relaunch Safari to test until you find the incompatible extension then click uninstall.