Unfortunately, deleting the com.apple.safari.plist didn't solve my original problem. Safari is still so superslow sometimes. And then its fast again. But Chrome is always faster and immediately responding. I've run a test with Etresoft:
Problem description:
generally laggy system. especially the finder
EtreCheck version: 2.1.2 (105)
Report generated 15. Dezember 2014 17:24:18 MEZ
Hardware Information: ℹ️
MacBook Pro (Retina, Mid 2012) (Verified)
MacBook Pro - model: MacBookPro10,1
1 2.3 GHz Intel Core i7 CPU: 4-core
8 GB RAM Not upgradeable
BANK 0/DIMM0
4 GB DDR3 1600 MHz ok
BANK 1/DIMM0
4 GB DDR3 1600 MHz ok
Bluetooth: Good - Handoff/Airdrop2 supported
Wireless: en0: 802.11 a/b/g/n
Video Information: ℹ️
Intel HD Graphics 4000 -
Color LCD spdisplays_2880x1800Retina
NVIDIA GeForce GT 650M - VRAM: 1024 MB
System Software: ℹ️
OS X 10.10.1 (14B25) - Uptime: 16:57:59
Disk Information: ℹ️
APPLE SSD SM256E disk0 : (251 GB)
S.M.A.R.T. Status: Verified
EFI (disk0s1) <not mounted> : 210 MB
Recovery HD (disk0s3) <not mounted> [Recovery]: 650 MB
Macintosh HD (disk1) / : 249.79 GB (67.15 GB free)
Encrypted AES-XTS Unlocked
Core Storage: disk0s2 250.14 GB Online
USB Information: ℹ️
Apple Inc. FaceTime HD Camera (Built-in)
Apple Inc. BRCM20702 Hub
Apple Inc. Bluetooth USB Host Controller
Apple Inc. Apple Internal Keyboard / Trackpad
Thunderbolt Information: ℹ️
Apple Inc. thunderbolt_bus
Gatekeeper: ℹ️
Mac App Store and identified developers
Kernel Extensions: ℹ️
/Library/Extensions
[not loaded] com.numark.4trak.usb (3.0.2 - SDK 10.7) [Support]
Startup Items: ℹ️
TuxeraNTFSUnmountHelper: Path: /Library/StartupItems/TuxeraNTFSUnmountHelper
Startup items are obsolete in OS X Yosemite
Launch Agents: ℹ️
[loaded] org.macosforge.xquartz.startx.plist [Support]
Launch Daemons: ℹ️
[loaded] com.adobe.fpsaud.plist [Support]
[loaded] com.microsoft.office.licensing.helper.plist [Support]
[loaded] org.macosforge.xquartz.privileged_startx.plist [Support]
User Launch Agents: ℹ️
[loaded] com.google.keystone.agent.plist [Support]
[running] com.spotify.webhelper.plist [Support]
User Login Items: ℹ️
iTunesHelper Programm (/Applications/iTunes.app/Contents/MacOS/iTunesHelper.app)
NIHardwareAgent ProgrammHidden (/Library/Application Support/Native Instruments/Hardware/NIHardwareAgent.app)
Dropbox Programm (/Applications/Dropbox.app)
Internet Plug-ins: ℹ️
FlashPlayer-10.6: Version: 16.0.0.235 - SDK 10.6 [Support]
QuickTime Plugin: Version: 7.7.3
Flash Player: Version: 16.0.0.235 - SDK 10.6 [Support]
Default Browser: Version: 600 - SDK 10.10
SharePointBrowserPlugin: Version: 14.4.6 - SDK 10.6 [Support]
Silverlight: Version: 5.1.30514.0 - SDK 10.6 [Support]
JavaAppletPlugin: Version: 15.0.0 - SDK 10.10 Check version
Safari Extensions: ℹ️
AdBlock
Audio Plug-ins: ℹ️
Numark4TrakAudioHAL: Version: Unknown - SDK 10.7 [Support]
3rd Party Preference Panes: ℹ️
Flash Player [Support]
Tuxera NTFS [Support]
Time Machine: ℹ️
Mobile backups: OFF
Auto backup: YES
Volumes being backed up:
Macintosh HD: Disk size: 249.79 GB Disk used: 182.64 GB
Destinations:
Backup [Local]
Total size: 251.20 GB
Total number of backups: 3
Oldest backup: 2014-12-07 16:51:16 +0000
Last backup: 2014-12-14 19:12:26 +0000
Size of backup disk: Too small
Backup size 251.20 GB < (Disk used 182.64 GB X 3)
Top Processes by CPU: ℹ️
8% WindowServer
1% hidd
1% SoulseekQt
1% Dock
0% fontd
Top Processes by Memory: ℹ️
318 MB com.apple.WebKit.WebContent
266 MB Safari
258 MB Preview
137 MB Finder
129 MB WindowServer
Virtual Memory Information: ℹ️
1.33 GB Free RAM
4.62 GB Active RAM
1.18 GB Inactive RAM
1.23 GB Wired RAM
4.93 GB Page-ins
2 MB Page-outs
Diagnostics Information: ℹ️
Dec 15, 2014, 12:26:53 AM Self test - passed