Font Book is a font manager, but third party managers are not, and never are directly the cause. What you're seeing is the font LastResort. The OS uses this when either a font it needs to use for the text is badly damaged, or much more frequently, the font cache data is trashed. The simplest approach to try first is to clear the font cache files.
Close all running applications. From an administrator account, open the Terminal app and enter the following command. You can also copy/paste it from here into the Terminal window:
sudo atsutil databases -remove
Terminal will then ask for your admin password. As you type, it will not show anything, so be sure to enter it correctly.
This removes all font cache files. Both for the system and the current logged in user account. After running the command, close Terminal and immediately restart your Mac.