You may get more answers in the Mac Pro section, rather than here, which is for PowerPC Macs from 10 years ago or more.
You may need to format the drive in an external enclosure, or using the version of DIsk Utility that came with Snow Leopard, due to a bug introduced in 10.8.4, which I do not believe has been fixed. It's described in this discussion:
http://apple.stackexchange.com/questions/112266/why-doesnt-my-mac-pro-see-my-new -4tb-sata-drive
I recently installed a 3 TB drive in a drive bay of my 2008 Mac Pro. When I rebooted it was not recognised and required formatting. However Disk Utility formatted it as a “Logical Volume Group”. I could not set the partition and GUID option and it was not showing the full capacity of the drive.
I Googled the issue and found that 10.8.4 and 10.8.5 have a bug which was causing this problem to occur with drives of 3 TB and greater capacity. The solution was to boot from an earlier version of OS X. I booted from a Snow Leopard boot drive which I keep on a USB Flash Drive and used Disk Utility to successfully re-format and partition the 3 TB drive. I am not sure whether the bug is still present in Mavericks.
I was running 10.8.5 when I encountered the problem I described above - drive not recognised but Disk Utility did offer to format it. However the normal format options were not available with "Logical Volume Group" being the only option.
I did not have a boot volume pre 10.8.4 but did have a Snow Leopard boot volume. When I restarted my Mac Pro with this Snow Leopard volume I was able to use Disk Utility to set the drive to one partition and GUID format. When I rebooted into 10.8.5 the drive was recognised as a normal volume and I have been using it for my Time Machine backup ever since.
Also, I believe that on at least some 6TB drives, the screw holes are in different locations on the drive and this makes it difficult to mount them in the drive sleds. This might only be a problem with Seagate 6TB drives, though. If you want the drive in BD Aqua's link, check with OWC about whether the screw holes are in the expected positions.