Safari/Firefox can't connect to the server
I am trying to troubleshoot an issue, which prevents a browser (Safari, Firefox, Chrome, Opera) from accessing a website...given that the same message appears "..can't connect to the server. Can't open the page "http://www.." because ...can't connect to the server", but that neither Macscan nor Sophos have been able to identify any Virus/Mailware/Spyware related issues, is this issue likely to be other than a virus/spyware/mailware.
Mac mini, iOS 5, Mac OS 10.5.8