Can anyone help me with error "TLB invalidation IPI timeout"?

I periodically have my Macbook 3,1 freeze up and demand that I shut it down. I have (silly me) ignored it until now because now it is happening more frequently.

Here is the panic report:

Interval Since Last Panic Report: 611917 sec

Panics Since Last Report: 2

Anonymous UUID: 9806BFD2-6B49-41B1-83CB-3D2347DEE8B3

Tue Feb 3 14:11:33 2015

panic(cpu 1 caller 0x28fc2e): "TLB invalidation IPI timeout: " "CPU(s) failed to respond to interrupts, unresponsive CPU bitmap: 0x0, NMIPI acks: orig: 0x0, now: 0x0"@/SourceCache/xnu/xnu-1504.15.3/osfmk/i386/pmap.c:3572

Backtrace (CPU 1), Frame : Return Address (4 potential args on stack)

0x431f3858 : 0x21b837 (0x5dd7fc 0x431f388c 0x223ce1 0x0)

0x431f38a8 : 0x28fc2e (0x59a47c 0x0 0x0 0x0)

0x431f3918 : 0x292d36 (0x84b7a0 0x5c2bb000 0x0 0xe678dc)

0x431f39c8 : 0x26c3de (0x7d63a 0x0 0xd42eebcb 0x71c)

0x431f3a68 : 0x26157b (0xb7dfd4c 0x0 0x0 0x2f6000)

0x431f3b98 : 0x261b4b (0x5c4dc000 0x0 0x0 0x0)

0x431f3bd8 : 0x283c4f (0x6dd2ae4 0x5c1e6000 0x0 0x5c4dc000)

0x431f3c38 : 0x55e363 (0x6dd2ae4 0x5c1e6000 0x0 0x2f6000)

0x431f3c88 : 0x55e06c (0x11043b00 0x23c1ebc 0x10f09300 0x0)

0x431f3ca8 : 0x55dd05 (0x10f09300 0x301 0x44399ac 0x0)

0x431f3cc8 : 0x55d32c (0x10f09300 0x0 0x2 0x4)

0x431f3ce8 : 0x506769 (0x10f09300 0x0 0x431f3d18 0x5091a3)

0x431f3d08 : 0x5577b2 (0x10f09300 0x4 0x431f3d38 0x506ad1)

0x431f3d58 : 0x50674e (0x11043b00 0x0 0x1 0x11612e00)

0x431f3d78 : 0x506769 (0x11043b00 0x0 0x52d8000 0x506ad1)

0x431f3d98 : 0xe9b28e (0x11043b00 0x11612e00 0x6b3bc04 0x1)

0x431f3dd8 : 0xe9b474 (0x35f96000 0x11612e00 0x431f3e08 0x35f96000)

0x431f3e08 : 0xe9b3fd (0x35f96000 0x0 0x11612e00 0x84baa0)

0x431f3e38 : 0xe9b22a (0x35f96000 0x0 0x6665800 0x35f96000)

0x431f3e78 : 0xe865d2 (0x35f96000 0xf09c800 0x431f3eb8 0x226b39)

0x431f3eb8 : 0xe86621 (0x35f96000 0x0 0x1 0x2a0577)

0x431f3ed8 : 0x553ec7 (0x35f96000 0x6b00b80 0x1 0x2275c6)

0x431f3f28 : 0x552ea6 (0x6b00b80 0x0 0x0 0x0)

0x431f3f88 : 0x552eea (0x6c4bf80 0x863ea0 0x0 0xffffffff)

0x431f3fc8 : 0x2a179c (0x6c4bf80 0x0 0x10 0x815ff44)

Kernel Extensions in backtrace (with dependencies):

com.apple.driver.AppleIntelGMA950(6.3.6)@0xe83000->0xeb9fff

dependency: com.apple.iokit.IOPCIFamily(2.6.5)@0x949000

dependency: com.apple.iokit.IONDRVSupport(2.2.1)@0xc14000

dependency: com.apple.iokit.IOGraphicsFamily(2.2.1)@0xbf2000

BSD process name corresponding to current thread: kernel_task

Mac OS version:

10K549

Kernel version:

Darwin Kernel Version 10.8.0: Tue Jun 7 16:33:36 PDT 2011; root:xnu-1504.15.3~1/RELEASE_I386

System model name: MacBook2,1 (Mac-F4208CAA)

System uptime in nanoseconds: 7821766691477

unloaded kexts:

com.apple.driver.AppleFileSystemDriver 2.0 (addr 0xcb5000, size 0x12288) - last unloaded 95757643828

loaded kexts:

org.virtualbox.kext.VBoxNetAdp 4.3.10 - last loaded 32023653716

org.virtualbox.kext.VBoxNetFlt 4.3.10

org.virtualbox.kext.VBoxUSB 4.3.10

org.virtualbox.kext.VBoxDrv 4.3.10

com.Cycling74.driver.Soundflower 1.6.6

com.apple.filesystems.autofs 2.1.0

com.apple.driver.AudioAUUC 1.57

com.apple.driver.AppleHDA 2.0.5f14

com.apple.Dont_Steal_Mac_OS_X 7.0.0

com.apple.driver.AudioIPCDriver 1.1.6

com.apple.driver.AppleUpstreamUserClient 3.5.7

com.apple.driver.AppleMCCSControl 1.0.20

com.apple.driver.SMCMotionSensor 3.0.1d2

com.apple.driver.AppleIntelMeromProfile 19

com.apple.driver.ACPI_SMC_PlatformPlugin 4.7.0a1

com.apple.driver.AirPort.Atheros21 425.14.7

com.apple.driver.AppleIntelGMA950 6.3.6

com.apple.driver.AppleLPC 1.5.1

com.apple.driver.AppleIntelIntegratedFramebuffer 6.3.6

com.apple.driver.AppleBacklight 170.0.46

com.apple.driver.AppleUSBTrackpad 201.6

com.apple.driver.AppleUSBTCKeyEventDriver 201.6

com.apple.driver.AppleUSBTCKeyboard 201.6

com.apple.driver.AppleIRController 303.8

com.apple.iokit.SCSITaskUserClient 2.6.8

com.apple.iokit.AppleYukon2 3.2.1b1

com.apple.iokit.IOAHCIBlockStorage 1.6.4

com.apple.driver.AppleAHCIPort 2.1.7

com.apple.BootCache 31.1

com.apple.AppleFSCompression.AppleFSCompressionTypeZlib 1.0.0d1

com.apple.driver.AppleIntelPIIXATA 2.5.1

com.apple.driver.AppleUSBHub 4.2.4

com.apple.driver.AppleFWOHCI 4.7.3

com.apple.driver.AppleUSBEHCI 4.2.4

com.apple.driver.AppleSmartBatteryManager 160.0.0

com.apple.driver.AppleEFINVRAM 1.4.0

com.apple.driver.AppleRTC 1.3.1

com.apple.driver.AppleHPET 1.5

com.apple.driver.AppleUSBUHCI 4.2.0

com.apple.driver.AppleACPIButtons 1.3.6

com.apple.driver.AppleSMBIOS 1.7

com.apple.driver.AppleACPIEC 1.3.6

com.apple.driver.AppleAPIC 1.4

com.apple.driver.AppleIntelCPUPowerManagementClient 142.6.0

com.apple.security.sandbox 1

com.apple.security.quarantine 0

com.apple.nke.applicationfirewall 2.1.14

com.apple.driver.AppleIntelCPUPowerManagement 142.6.0

com.apple.driver.AppleProfileReadCounterAction 17

com.apple.driver.AppleProfileTimestampAction 10

com.apple.driver.AppleProfileThreadInfoAction 14

com.apple.driver.AppleProfileRegisterStateAction 10

com.apple.driver.AppleProfileKEventAction 10

com.apple.driver.AppleProfileCallstackAction 20

com.apple.driver.DspFuncLib 2.0.5f14

com.apple.iokit.IOSurface 74.2

com.apple.iokit.IOBluetoothSerialManager 2.4.5f3

com.apple.iokit.IOSerialFamily 10.0.3

com.apple.iokit.IOAudioFamily 1.8.3fc2

com.apple.kext.OSvKernDSPLib 1.3

com.apple.iokit.IOFireWireIP 2.0.3

com.apple.driver.AppleHDAController 2.0.5f14

com.apple.iokit.IOHDAFamily 2.0.5f14

com.apple.iokit.AppleProfileFamily 41

com.apple.driver.AppleSMC 3.1.0d5

com.apple.driver.IOPlatformPluginFamily 4.7.0a1

com.apple.iokit.IO80211Family 320.1

com.apple.driver.AppleBacklightExpert 1.0.1

com.apple.iokit.IONDRVSupport 2.2.1

com.apple.iokit.IOGraphicsFamily 2.2.1

com.apple.driver.CSRUSBBluetoothHCIController 2.4.5f3

com.apple.driver.AppleUSBBluetoothHCIController 2.4.5f3

com.apple.iokit.IOBluetoothFamily 2.4.5f3

com.apple.driver.AppleUSBMergeNub 4.2.4

com.apple.iokit.IOUSBHIDDriver 4.2.0

com.apple.driver.AppleUSBComposite 3.9.0

com.apple.iokit.IOSCSIMultimediaCommandsDevice 2.6.8

com.apple.iokit.IOBDStorageFamily 1.6

com.apple.iokit.IODVDStorageFamily 1.6

com.apple.iokit.IOCDStorageFamily 1.6.1

com.apple.driver.XsanFilter 402.1

com.apple.iokit.IOATAPIProtocolTransport 2.5.1

com.apple.iokit.IOSCSIArchitectureModelFamily 2.6.8

com.apple.iokit.IOAHCIFamily 2.0.6

com.apple.iokit.IONetworkingFamily 1.10

com.apple.iokit.IOATAFamily 2.5.1

com.apple.iokit.IOUSBUserClient 4.2.4

com.apple.iokit.IOFireWireFamily 4.2.6

com.apple.driver.AppleEFIRuntime 1.4.0

com.apple.iokit.IOUSBFamily 4.2.4

com.apple.iokit.IOHIDFamily 1.6.6

com.apple.iokit.IOSMBusFamily 1.1

com.apple.kext.AppleMatch 1.0.0d1

com.apple.security.TMSafetyNet 6

com.apple.driver.DiskImages 289.1

com.apple.iokit.IOStorageFamily 1.6.3

com.apple.driver.AppleACPIPlatform 1.3.6

com.apple.iokit.IOPCIFamily 2.6.5

com.apple.iokit.IOACPIFamily 1.3.0

Model: MacBook2,1, BootROM MB21.00A5.B07, 2 processors, Intel Core 2 Duo, 2.16 GHz, 4 GB, SMC 1.17f0

Graphics: Intel GMA 950, GMA 950, Built-In, spdisplays_integrated_vram

Memory Module: global_name

AirPort: spairport_wireless_card_type_airport_extreme (0x168C, 0x87), Atheros 5416: 2.1.14.6

Bluetooth: Version 2.4.5f3, 2 service, 12 devices, 1 incoming serial ports

Network Service: AirPort, AirPort, en1

Serial ATA Device: WDC WD5000LPVX-28V0TT0, 465.76 GB

Parallel ATA Device: MATSHITADVD-R UJ-857R

USB Device: Built-in iSight, 0x05ac (Apple Inc.), 0x8501, 0xfd400000 / 2

USB Device: Bluetooth USB Host Controller, 0x05ac (Apple Inc.), 0x8205, 0x7d100000 / 2

USB Device: IR Receiver, 0x05ac (Apple Inc.), 0x8240, 0x5d200000 / 2

USB Device: Apple Internal Keyboard / Trackpad, 0x05ac (Apple Inc.), 0x021a, 0x1d200000 / 2