Will I lose video quality if I combine clips multiple times?

Say for instance I have videos A and B, and I combine them to make video C. Later on, I shoot videos D and E, and I combine them to make video F. Now I want to combine C and F together to make a final video.

My question is: Will I lose HD quality if I combine clips over and over again? Will the quality of video F be the same as the originals?

Thanks!