iTunes still won't open after latest updated to fix it.
April 19 update was supposed to be a fix for apps that wouldn't open, but it didn't work. I still have to open iTunes with the terminal.
iMac, iOS 8.3
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According to multiple reports on this site, Apple Support has given the following instructions to others who had a similar problem. I can't confirm that this procedure works or that it's necessary, but it won't leave you any worse off than you are now.
First, back up all data.
Select the iTunes icon in the Applications folder and open the Info window. Click the padlock icon in the lower right corner to unlock the settings.
In the Sharing & Permissions section, change the Privilege setting for each Name in the list to Read & Write. Close the window. If the settings aren't visible, click the disclosure triangle on the left so that it points down.
You should now be able to drag the iTunes application to the Trash and empty. Your iTunes data won't be affected.
Click the iTunes link at the top of this page, download the installer package and run it.
If iTunes still doesn't launch, or if you can't complete the procedure, reinstall the OS.