Mac 10.6.8 safari upgrade. Will upgrading to Maverick cause other issues?

I need to upgrade Safari 5.1.10 on Mac 10.6.8 Snow Leopard to a newer version. My concern is that other issues will pop up with other apps and peripherals if I upgrade to Maverick or Mountain Lion...Please advise.

other info:

Model Name: iMac

Model Identifier: iMac10,1

Processor Name: Intel Core 2 Duo

Processor Speed: 3.06 GHz

Number Of Processors: 1

Total Number Of Cores: 2

L2 Cache: 3 MB

Memory: 4 GB