Questions about Mini with dual drives

Hi. I'm interested in buying a used Mac Mini that I saw posted on Craigs List. It's from 2011 and has two internal drives: a 128GB SSD drive and a 500GB normal hard drive.

My questions are these:

On my current Mac, my Applications folder is 30GB and my user folder is 200GB. So I can't fit all of my files on the 128GB SSD of the Mac Mini.

So, it is possible to split up my user files and my applications between the two drives on the Mac Mini?

Could I put my Applications folder on the SSD drive, and my Documents folder on the SSD drive, but put all my other folders, including the rest of my user files, on the 500GB drive? Or do all those folders need to be on the same volume?

Also, can I use Time Machine to back up both drives at once on one external drive?

Thanks!

Mirsky