Ideal Mac Pro 4,1 upgrades -- cost vs benefit
Hi all,
I would love some input on what to upgrade for my Mac Pro 4,1 to squeeze the most out of it performance wise for a fixed budget of about $3K. I'm leaning towards an internal PCIe RAID card + a bunch of SSD and spinning disks. My current configuration is as follows (* next to what I am contemplating upgrading / replacing).
Mac Pro 4,1
Yosemite 10.10.3
2x2.93 Dual Quad Core processors
64 GB OWC 1066 RAM
Apple Raid Card (*)
NewTech Esata Card (*)
NVIDIA GeForce GT 120 (*)
Dual OWC Mercury EXTREME Pro SSD RAID 0 -- Optical Bay using Softraid*
Quad Hitachi Hds722020ala330 2TB Hard Drive, 7200rpm, SATA 3.5 -- connected to Apple Raid Card as 4 terabyte RAID 0-1*
Dual monitors (Apple 30" and Apple 23").
External Drobo S currently with 5 2 TB commodity drives
Many external hard-drives !!! in enclosures or bare with a NewTech Voyager Q reader
I've looked at these and other forums for CPU, SSD, PCIe Host adapter and PCIe Blades. My question is given a particular starting point, what is the best bang-for-the-buck for my particular use case (see below "USE CASE"). I do notice my disk I/O is particularly slow with about 200 MB/S read/write on the 4TB spinning platter RAID and some severe wait times loading and unloading Genomics data or large Aperture Libraries so I'm definitely going to get rid of the Apple Raid card!
Short of buying a new MacPro and maxing it out I'd like to really upgrade the current machine to last for at least another 3 years (maybe even 4 which would put it close to a 10 year lifespan!).
I would love suggestions on these potential choices:
Speed and expand the internal I/O + storage
*Areca PCI mini-sas RAID card with two internal sas to sata ports connected to both
*4x1TB SSDs in optical bay
*4x4TB platters in raid 01 in standard bay with known vendor solution
Some combination of above + PCIE blade like Samsung XP941 SM951?
Buy a new video card for parallel processing (which one would be a great price / cuda performance)...
Get a faster externally facing PCIE Sas Card to connect to a raid exclosure + future proof data?
Maybe use all the extra 2TB drives I will have laying around in some sort of cold-storage idea...
Thanks for your thoughts and sorry for the long post!
***USE CASE
I am a scientist and photographer and my use case is basically 50% big data (genomics, remote sensing) workstation with parallel processing and disk I/O important (possible use of CUDA in future but not a priority now) and the rest a very large digital photography collection, photo programs include the aging Aperture and a future forced switch to alternative products. I'd like all my highly accessed data organized well and onboard my home directory. I'd like blazingly fast access to genomic data for I/O, both sequential reads and writes as well as random I/O. Genomic data sets can be up to a terabyte. I would also like very fast access to my photo libraries. I'd like internal redundancy and external Time Machine Backup.
Mac Pro, OS X Yosemite (10.10.3)