When I go to click a drop down menu, Safari either reloads the page or says it's unavailable?

Might be a cookies, cache, extensions, or plug-ins issue.

From your Safari menu bar click Safari > Preferences then select the Privacy tab.

Click: Remove All Website Data

Then delete the cache.

Open a Finder window. From the Finder menu bar click Go > Go to Folder

Type or copy paste the following

~/Library/Caches/com.apple.Safari/Cache.db

Click Go then move the Cache.db file to the Trash.

Quit and relaunch Safari to test.

If that didn't help, from the Safari menu bar click Safari > Preferences then select the Extensions tab. Turn that OFF, quit and relaunch Safari to test.

If that helped, turn one extension on then quit and relaunch Safari to test until you find the incompatible extension then click uninstall.

If it's not an extensions issue, try troubleshooting third party plug-ins.

Back to Safari > Preferences. This time select the Security tab. Deselect: Allow plug-ins. Quit and relaunch Safari to test.

If that made a difference, instructions for troubleshooting plugins here.

What happens if you do a Get Info (command - I) on the file? Do you have read/write permissions? If not, unlock the padlock and set your permissions to read/write.

You forgot to tell us what version of Safari and OS X you are running.

Are you sure you are looking in the User Library? I just checked in Snow Leopard and I have the cache file there.