What is the best App for cleaning my Mac OS X Yosemite?

There is none, and none is needed. Your Mac doesn't require "cleaning."

Many, if not most, "cleaning" tools for a Mac cause more issues than they solve. The following link, in particular the "Free hard drive space" section has some good information that may be worth reading: http://www.thesafemac.com/mpg/

That may just be an issue with your accounting software's data management. But in and of itself that is no indication that the computer is slow.

Ways to help make a slow Mac faster

17 Reasons Why Your Mac Runs Slower Than it Should

Slow Mac Performance? This Article Solves It!

Fix slow start-ups in OS X | MacFixIt - CNET Reviews

6 Easy Tips to Speed Up OS X Yosemite on Your Mac

Avoid using any third-party software that claims to clean up your computer. Usually this software does more bad than good. Furthermore, you don't need it. Note that all computers will become slower over time even under normal use. Experienced users typically erase the hard drive and do a clean install from scratch at least once a year or whenever installing a major OS upgrade. Of course doing so also means you must maintain regular and multiple backups.

Add more RAM or cut back on the number of concurrently running applications and utilities. Remove unnecessary software such as anti-malware and software that promises to clean your Mac. Check for runaway processes: Runaway applications can shorten battery runtime, affect performance, and increase heat and fan acti… Also see:

Mavericks and later

Open Activity Monitor in the Utilities folder. Select All Processes from the View menu. Click on the CPU tab in the toolbar. Click twice on the %CPU column header to display in descending order. If you find a process using a large amount of %CPU, then select the process and click on the Quit icon in the toolbar. Click on the Force Quit button to kill the process. See if that helps. Be sure to note the name of the runaway process so you can track down the cause of the problem.

If this is a problem that has arisen since upgrading to Yosemite, then you might try this:

Reinstalling OS X Without Erasing the Drive

Boot to the Recovery HD: Restart the computer and after the chime press and hold down the COMMAND and R keys until the menu screen appears.

Repair the Hard Drive and Permissions: Upon startup select Disk Utility from the main menu. Repair the Hard Drive and Permissions as follows.

When the recovery menu appears select Disk Utility and press the Continue button. After Disk Utility loads select the indented Macintosh HD entry from the the left side list. Click on the First Aid tab, then click on the Repair Disk button. If Disk Utility reports any errors that have been fixed, then re-run Repair Disk until no errors are reported. If no errors are reported click on the Repair Permissions button. Wait until the operation completes, then quit Disk Utility and return to the main menu.

Reinstall OS X: Select Reinstall OS X and click on the Continue button.

Note: You will need an active Internet connection. I suggest using Ethernet if possible because it is three times faster than wireless and more reliable.

Alternatively, see:

Reinstall OS X Without Erasing the Drive

Choose the version you have installed now:

OS X Yosemite- Reinstall OS X

OS X Mavericks- Reinstall OS X

OS X Mountain Lion- Reinstall OS X

OS X Lion- Reinstall Mac OS X

Note: You will need an active Internet connection. I suggest using Ethernet

if possible because it is three times faster than wireless.

Please download and install EtreCheck from http://www.etresoft.com/etrecheck

Run it and post the report here.

When you see a beachball cursor or the slowness is especially bad, note the exact time: hour, minute, second.

These instructions must be carried out as an administrator. If you have only one user account, you are the administrator.

Launch the Console application in any of the following ways:

☞ Enter the first few letters of its name into a Spotlight search. Select it in the results (it should be at the top.)

☞ In the Finder, select Go ▹ Utilities from the menu bar, or press the key combination shift-command-U. The application is in the folder that opens.

☞ Open LaunchPad and start typing the name.

The title of the Console window should be All Messages. If it isn't, select

SYSTEM LOG QUERIES ▹ All Messages

from the log list on the left. If you don't see that list, select

View ▹ Show Log List

from the menu bar at the top of the screen.

Each message in the log begins with the date and time when it was entered. Scroll back to the time you noted above.

Select the messages entered from then until the end of the episode, or until they start to repeat, whichever comes first.

Copy the messages to the Clipboard by pressing the key combination command-C. Paste into a reply to this message by pressing command-V.

The log contains a vast amount of information, almost all of it useless for solving any particular problem. When posting a log extract, be selective. A few dozen lines are almost always more than enough.

Please don't indiscriminately dump thousands of lines from the log into this discussion.

Please don't post screenshots of log messages—post the text.

Some private information, such as your name, may appear in the log. Anonymize before posting.

When you post the log extract, you might see an error message on the web page: "You have included content in your post that is not permitted," or "The message contains invalid characters." That's a bug in the forum software. Please post the text on Pastebin, then post a link here to the page you created.