After App Store update to iTunes 12.2.2.25 and OSX 10.10.5 I started getting the spinning, hanging colorwheel ("iTunes Not Responding") for the first time since I bought this computer.
Here is the last error log (I have 6 more this morning if you need them):
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Date/Time: 2015-08-15 10:25:41 -0400
OS Version: 10.10.5 (Build 14F27)
Architecture: x86_64
Report Version: 21
Command: iTunes
Path: /Applications/iTunes.app/Contents/MacOS/iTunes
Version: 12.2.2 (12.2.2.25)
Build Version: 2
Project Name: iTunes
Source Version: 1200012002002025
Parent: launchd [1]
PID: 830
Event: hang
Duration: 2.90s (process was unresponsive for 837 seconds before sampling)
Steps: 30 (100ms sampling interval)
Hardware model: Macmini6,1
Active cpus: 4
Fan speed: 1799 rpm
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Timeline format: stacks are sorted chronologically
Use -i and -heavy to re-report with count sorting
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Heaviest stack for the main thread of the target process:
30 ??? (iTunes + 9140) [0x1090143b4]
30 ??? (iTunes + 8820998) [0x10987b906]
30 -[NSApplication run] + 594 (AppKit + 551667) [0x7fff86e24af3]
30 -[NSApplication nextEventMatchingMask:untilDate:inMode:dequeue:] + 346 (AppKit + 593496) [0x7fff86e2ee58]
30 _DPSNextEvent + 978 (AppKit + 596139) [0x7fff86e2f8ab]
30 _BlockUntilNextEventMatchingListInModeWithFilter + 71 (HIToolbox + 205099) [0x7fff9011612b]
30 ReceiveNextEventCommon + 431 (HIToolbox + 205546) [0x7fff901162ea]
30 RunCurrentEventLoopInMode + 235 (HIToolbox + 206191) [0x7fff9011656f]
30 CFRunLoopRunSpecific + 296 (CoreFoundation + 465880) [0x7fff92672bd8]
30 __CFRunLoopRun + 927 (CoreFoundation + 467391) [0x7fff926731bf]
30 __CFRunLoopDoSources0 + 269 (CoreFoundation + 469901) [0x7fff92673b8d]
30 __CFRUNLOOP_IS_CALLING_OUT_TO_A_SOURCE0_PERFORM_FUNCTION__ + 17 (CoreFoundation + 526849) [0x7fff92681a01]
30 ??? (iTunes + 9554288) [0x10992e970]
30 ??? (iTunes + 9554090) [0x10992e8aa]
30 ??? (iTunes + 9551074) [0x10992dce2]
30 ??? (iTunes + 8671225) [0x109856ff9]
30 ??? (iTunes + 6978505) [0x1096b9bc9]
30 ??? (iTunes + 6977458) [0x1096b97b2]
30 ??? (iTunes + 6980951) [0x1096ba557]
30 mach_msg_trap + 10 (libsystem_kernel.dylib + 70878) [0x7fff8d7f14de]
*30 ipc_mqueue_receive_continue + 0 (kernel + 1144832) [0xffffff8000317800]
Process: iTunes [830]
Path: /Applications/iTunes.app/Contents/MacOS/iTunes
Architecture: x86_64
Parent: launchd [1]
UID: 501
Task size: 48198 pages (-435)
CPU Time: 0.016s
Note: Unresponsive for 837 seconds before sampling