I just tried to open a photo in Preview, and print it out multiple times (6) on one page.
The preview in the printing pop-up then showed the photo taking up just one of the 6 spaces on the page.
I went to check the Preview help resource, and I was instructed to > choose File/Print, choose print options or if I don't see them (I didn't see them), click Show Details; then "To print the same image on page multiple times on a sheet of paper, click the 'Copies per page' pop-up menu, then choose a number."
Unfortunately, my print options don't seem to have any "Copies per page" selection. Maybe that "pop-up menu" is only apparent if I click on some hidden key in the print box? It DOES have fields where I can select "no. of copies" to print; and another menu of options for "layout", where I can select either 1,2,4,6,9, or 16 copies. But when I choose 6 copies, and also select a layout of 6 images to be printed on a single piece of paper, I still just get one small copy of my photo, on the upper-left-sixth of the page. My commands result in this one reduced photo being reprinted on 6 different sheets of paper.