karim Gad
While upgrading itunes to 12.2.2 for windows 10 this window appeared to me
iPhone 6, iOS 8.4.1
If an iTunes installation fails with the message "Error applying transforms. Verify that the specified transform paths are valid." this likely indicates that your language and regional preferences are not supported by the iTunes installer. Temporarily changing to a supported language should allow the installation to complete. Currently supported languages for install with iTunes 12.2.2.25 are: Catalan, Chinese, Croatian, Czech, Danish, Dutch, English, Finnish, French, German, Greek, Hebrew, Hungarian, Indonesian, Italian, Japanese, Korean, Malay, Norwegian, Polish, Portuguese, Romanian, Russian, Slovak, Spanish, Swedish, Thai, Turkish, Ukrainian, and Vietnamese. My guess is that your system is set to Arabic which has been the case for others with this problem.
tt2