The choice to use the Palm Desktop is clearly an individual one. It's not Sync Services compliant—and never will be—so it represents a now outmoded technology and a dead-end for future improvements. Palm has publicly declared its intent not to upgrade the package, beyond providing basic compatibility upgrades similar to the Palm Desktop 4.2.1 and 4.2.2 packages. This choice also precludes the use of iCal and the Address Book, but some users are quite happy with the way the Palm Desktop operates. Its strengths, to be fair, include the built-in memo synchronization function, and its handling of task or to do data.
From my experience, these are the preferred synchronization environments under Mac OS X 10.4 or later, in order of most effective to least:
• the Missing Sync for Palm OS
• iSync and the iSync Palm Conduit
• the Palm Desktop
The greatest benefit to using either the Missing Sync for Palm OS or iSync is their compatibility with the Sync Services framework, a technology explained here:
http://developer.apple.com/macosx/syncservices.html
A Bluetooth link work well for most users and it is convenient, but USB provides a wider, faster and far more secure data path, and is probably a better choice for virtually everyone, though few seem to recognize it as such.
I cannot help you with the error without you providing the specific error message.
You can back the address up in several ways, including approaches using the Backup conduit and backing up a copy of the user files created by the Palm Desktop.