sync issues with error 0xE8000065

Hello there, kranthi.

It seems you're receiving the message "iTunes could not connect to this [device] because an unknown error occurred (0xE8000065)" when syncing your iPhone 5s. The following Knowledge Base article offers up some great, in-depth steps for troubleshooting this error:

iOS: Unknown error containing ‘0xE‘ when connecting to a Windows PC

The following steps may resolve the issue.

Note: If you use a Mac and see these symptoms, follow this article.

1. Restart your computer.
2. Install the latest version of iTunes.
3. Verify that your computer meets the minimum system requirements. iOS devices require the following minimum version of Windows:
   • Windows XP Service Pack 3
   • Windows Vista
   • Windows 7
   • Windows 8
4. Download and install any available software updates from Microsoft.
5. Connect the device directly to your computer; not to an external USB hub.
6. Check that the Dock Connector or Lightning Connector on both the device and cable are clean of any lint or other debris. If possible, connect your device using a different Apple 30-pin to USB cable or Apple Lightning Connector to USB cable.
7. Disconnect other USB peripherals from your computer, with the exception of your keyboard and mouse. After disconnecting these peripherals, restart your computer, connect your device, and open iTunes.
8. Connect your device to a different USB port on your computer.
9. Use the Task Manager to stop some Apple Services:
   1. Launch the Task Manager:
      • For Windows XP: Press

        Control + alt + delete

        on the keyboard.
      • For Windows Vista, Windows 7 and Windows 8: Press

        Control + alt + delete

        on the keyboard. Then click "Start Task Manager". If Windows needs your permission to continue, click "Continue".
   2. Click the Processes tab of the Task Manager. End each of these three processes by clicking in their names and choosing "End Process":
      • iTunesHelper.exe
      • AppleMobileDeviceService.exe
      • iPodService.exe
   3. After ending these processes, reboot your computer, open iTunes, and test.
10. Connect your device to a different computer to determine whether the issue is specific to your computer.

    If the issue occurs on only one computer

    1. Sometimes outdated drivers on a Windows computer can cause this issue. Check with the manufacturer of your computer, or your computer's motherboard, for any available USB chipset driver updates. Learn more about updating drivers for Windows.
    2. Determine if the issue affects a specific Windows user account or all accounts. Follow the steps below to create a new user account depending on your operating system:
       • Windows XP: Follow the steps in this Microsoft article.
       • Windows Vista or Windows 7: Follow the steps in this Microsoft article.
       • Windows 8: Follow the steps in this Microsoft article.
    3. If the issue persists in more than one user, uninstall and reinstall iTunes.
       • Windows XP
       • Windows Vista, Windows 7 or Windows 8

       If you have trouble while uninstalling or reinstalling iTunes, follow the steps in this article.

    4. Disabling Power Management of your USB root hubs may work around or resolve the issue.
    5. In some cases, outdated or improperly configured security software may be causing the issue. Troubleshoot issues that may be caused by third-party security software.

    If the issue occurs on multiple computers

    1. Make sure you have tried a different, known-good, Apple 30-pin to USB cable or Apple Lightning Connector to USB cable.
    2. If the computers on which you have tested your device are from the same brand and were perhaps purchased at the same time, it is possible that the cause of the issue is still computer specific. This might be the case if you tested multiple computers in a business environment.
       • Check with the manufacturer of your computer or the system administrator of your company for any available USB chipset driver updates.
       • If the computers tested were configured by a system administrator, or if you configured multiple computers at home with the same software, it is possible that outdated or improperly configured security software may be the cause of the issue. Troubleshoot issues that may be caused by third-party security software.
    3. In some cases it may be necessary to restore the device, especially if the issue occurs on more than one computer and all of the above steps have been performed.
       1. Restoring the device will erase all data from it. If your device has an Internet connection, you may use email to send yourself your pictures, notes, and other data you may need to back up before you perform a restore.
       2. If you have backed up your device in the past and you wish to keep this backup, make a copy of the backup on your computer. See this article for details on where backups are stored.
       3. Follow this article to restore the device. When the restore is finished, restore from your latest backup.
       4. If the issue returns, follow this article again and restore, setting up as a new device.
    4. If you have performed all of the steps in this article and you are still experiencing the issue, contact Apple or your wireless carrier, whichever provides phone support for your device. To find Apple's contact information in your country, refer to Contacting Apple for Support and Service. If you use an iPhone, find your wireless carrier. Wherever you live in the world, you can find your Apple support and service options.

       If there is an Apple Retail Store nearby, find the closest store and then make a reservation through the online Apple Store Concierge. Reservations are strongly recommended.

Thanks for being a part of Apple Support Communities.

Kind Regards.