Sound constantly disappearing on iMac
I have an iMac where the sound is output through a set of Personus Monitors via a Focusrite audio interface.
All worked perfectly since I installed over a year ago, however I now have an issue where the sound just disappears system wide. So whether it's playing a tune through iTunes or playing guitar through Amplitube the sound just goes. In order to rectify I have to restart the iMac everytime which is a pain as it closes applications I currently have open.
I've searched similar issues on the forum and google and I can't find anyone resolution specific to playing audio through external speakers.
Any comments as to how I resolve this persistent bug?
I should advise that the sound doesn't disappear whilst I'm actively using the iMac, it only ever goes if I wake up from sleep mode.
Cheers
iMac (21.5-inch, Late 2012)