No. I wish it did too. The Camera only works with iChat(AIM) and Yahoo Messenger. It dosen't work on MSN or Skype, they just don't support it on mac. But on iChat and Yahoo, the people you video chat with can have any kind of system(Windows or Mac). As long as they have the AIM or Yahoo Messenger of course. The camera also works with a few online web chat sites. I hope this helps.
As others have stated the iSight camera does indeed work with Skype. While it doesn't work with MSN there is a third party application that allows you to use the camera with MSN buddies. Check out
Mercury Messenger.
I'm still holding out for Adium to support video. That'll be sweet.
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iSight with Video chat
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