Thanks. I've included the report from Etrecheck below: I obviously need to free up some RAM!!
EtreCheck version: 2.9.3 (253)
Report generated 2016-02-12 16:06:40
Download EtreCheck from http://etrecheck.com
Runtime 6:29
Performance: Below Average
Problem: Beachballing
Description:
iMac (24 inch, early 2009), 2.66 Ghz Intel Core 2 Dup, NVIDIA GeForce 9400 256 Mb - for no apparent reason other than a random mouse click, the computer freezes for anything between a couple of minutes and maybe 15-20 minutes. It then unfreezes and will respond to any clicks made while it has been frozen.
I have started in 'safe' mode and disconnected external peripherals. It's still happening, but perhaps to a slightly lesser degree. The overall response is slow, with simple activities taking a long time. e.g. moving a small folder to a new location took nearly a minute to complete. Ejecting an external disk took a minute to complete etc.
This started when I upgraded to El Capitan and has been getting progressively worse since then.
Hardware Information: ⓘ
iMac (24-inch, Early 2009)
[Technical Specifications] - [User Guide] - [Warranty & Service]
iMac - model: iMac9,1
1 2.66 GHz Intel Core 2 Duo CPU: 2-core
4 GB RAM Upgradeable - [Instructions]
BANK 0/DIMM0
2 GB DDR3 1067 MHz ok
BANK 1/DIMM0
2 GB DDR3 1067 MHz ok
Bluetooth: Old - Handoff/Airdrop2 not supported
Wireless: en1: 802.11 a/b/g/n
Video Information: ⓘ
NVIDIA GeForce 9400 - VRAM: 256 MB
iMac 1920 x 1200
System Software: ⓘ
OS X El Capitan 10.11.3 (15D21) - Time since boot: about 4 hours
Disk Information: ⓘ
WDC WD6400AAKS-40H2B0 disk0 : (640.14 GB) (Rotational)
EFI (disk0s1) <not mounted> : 210 MB
Macintosh HD (disk0s2) / : 639.28 GB (88.58 GB free) - 5 errors
Drive failure!
Recovery HD (disk0s3) <not mounted> [Recovery]: 650 MB
OPTIARC DVD RW AD-5670S ()
USB Information: ⓘ
Apple Inc. Built-in iSight
Apple Inc. Keyboard Hub
Apple Inc. Apple Keyboard
Apple Inc. BRCM2046 Hub
Apple Inc. Bluetooth USB Host Controller
Apple Computer, Inc. IR Receiver
Gatekeeper: ⓘ
Mac App Store and identified developers
Kernel Extensions: ⓘ
/Applications/WD SmartWare/Extras/WD +TURBO Installer.app
[not loaded] com.wdc.driver.1394HP (1.0.6) [Support]
[not loaded] com.wdc.driver.USBHP (1.0.4) [Support]
/System/Library/Extensions
[loaded] com.logmein.driver.LogMeInSoundDriver (4.1.50f15) [Support]
[not loaded] com.techsmith.TACC (1.0.2 - SDK 10.8) [Support]
System Launch Agents: ⓘ
[killed] com.apple.AssetCacheLocatorService.plist
[killed] com.apple.CallHistoryPluginHelper.plist
[killed] com.apple.CallHistorySyncHelper.plist
[killed] com.apple.FolderActionsDispatcher.plist
[killed] com.apple.Maps.pushdaemon.plist
[killed] com.apple.Safari.SafeBrowsing.Service.plist
[killed] com.apple.SafariCloudHistoryPushAgent.plist
[killed] com.apple.cloudphotosd.plist
[killed] com.apple.cmfsyncagent.plist
[killed] com.apple.coreservices.appleid.authentication.plist
[killed] com.apple.coreservices.uiagent.plist
[killed] com.apple.gamed.plist
[killed] com.apple.icloud.fmfd.plist
[killed] com.apple.iconservices.iconservicesagent.plist
[killed] com.apple.pbs.plist
[killed] com.apple.printtool.agent.plist
[killed] com.apple.quicklook.plist
[killed] com.apple.recentsd.plist
[killed] com.apple.reversetemplated.plist
[killed] com.apple.scopedbookmarkagent.xpc.plist
[killed] com.apple.secinitd.plist
[killed] com.apple.spindump_agent.plist
[killed] com.apple.telephonyutilities.callservicesd.plist
[loaded] 162 Apple tasks
[running] 51 Apple tasks
23 processes killed due to insufficient RAM
System Launch Daemons: ⓘ
[killed] com.apple.AssetCacheLocatorService.plist
[killed] com.apple.GSSCred.plist
[killed] com.apple.MobileFileIntegrity.plist
[killed] com.apple.aslmanager.plist
[killed] com.apple.audio.systemsoundserverd.plist
[killed] com.apple.awdd.plist
[killed] com.apple.cache_delete.plist
[killed] com.apple.iconservices.iconservicesagent.plist
[killed] com.apple.iconservices.iconservicesd.plist
[killed] com.apple.ifdreader.plist
[killed] com.apple.installd.plist
[killed] com.apple.periodic-daily.plist
[killed] com.apple.secinitd.plist
[killed] com.apple.spindump.plist
[killed] com.apple.tccd.system.plist
[killed] com.apple.wdhelper.plist
[killed] com.apple.xpc.smd.plist
[loaded] 196 Apple tasks
[running] 74 Apple tasks
17 processes killed due to insufficient RAM
Launch Agents: ⓘ
[running] com.trusteer.rapport.rapportd.plist [Support]
Launch Daemons: ⓘ
[loaded] com.adobe.fpsaud.plist [Support]
[running] com.trusteer.rooks.rooksd.plist [Support]
User Login Items: ⓘ
apple-scc-20151102-162955 UNKNOWN (missing value)
Dropbox Application (/Applications/Dropbox.app)
Other Apps: ⓘ
[running] com.apple.xpc.launchd.oneshot.0x10000004.Microsoft Word
[running] com.apple.xpc.launchd.oneshot.0x10000007.EtreCheck
[running] com.getdropbox.dropbox.99872
[loaded] com.microsoft.Word.70112
[running] com.microsoft.autoupdate.fba.107552
Internet Plug-ins: ⓘ
LogMeInSafari64: Version: 1.0.586 [Support]
Google Earth Web Plug-in: Version: 5.1 [Support]
Default Browser: Version: 601 - SDK 10.11
Flip4Mac WMV Plugin: Version: 3.1.0.24 - SDK 10.8 [Support]
OfficeLiveBrowserPlugin: Version: 12.3.6 [Support]
Silverlight: Version: 5.1.40416.0 - SDK 10.6 [Support]
FlashPlayer-10.6: Version: 20.0.0.306 - SDK 10.6 [Support]
LogMeIn: Version: 1.0.586 [Support]
QuickTime Plugin: Version: 7.7.3
Flash Player: Version: 20.0.0.306 - SDK 10.6 [Support]
LogMeInSafari32: Version: 1.0.586 [Support]
SharePointBrowserPlugin: Version: 14.5.9 - SDK 10.6 [Support]
iPhotoPhotocast: Version: 7.0
Safari Extensions: ⓘ
Save to Pocket
3rd Party Preference Panes: ⓘ
Flash Player [Support]
Flip4Mac WMV [Support]
MyBusinessWorks [Support]
Perian [Support]
Trusteer Endpoint Protection [Support]
Time Machine: ⓘ
Skip System Files: NO
Mobile backups: OFF
Auto backup: YES
Volumes being backed up:
Macintosh HD: Disk size: 639.28 GB Disk used: 550.70 GB
Destinations:
My Book [Local]
Total size: 999.37 GB
Total number of backups: 38
Oldest backup: 27/11/2015, 16:09
Last backup: 12/02/2016, 10:30
Size of backup disk: Too small
Backup size 999.37 GB < (Disk used 550.70 GB X 3)
Top Processes by CPU: ⓘ
9% mds_stores
4% WindowServer
2% kernel_task
1% mdworker(11)
1% ps
Top Processes by Memory: ⓘ
481 MB kernel_task
479 MB com.apple.WebKit.WebContent(6)
315 MB mdworker(11)
160 MB Safari
147 MB Mail
Virtual Memory Information: ⓘ
66 MB Free RAM
4.18 GB Used RAM (825 MB Cached)
45 MB Swap Used
Diagnostics Information: ⓘ
Feb 12, 2016, 11:55:19 AM Self test - passed
Jan 21, 2016, 11:45:41 AM /Library/Logs/DiagnosticReports/Kernel_2016-01-21-114541_[redacted].panic [Details]