This absolutely works!! I have been researching for hours, but did not want to try all the bazaar remedies I found. And some back story here that may help some folks: I had two issues that this seems to have resolved - as they are related. First when I went to HELP / CHECK FOR UPDATES in iTunes, the results brought back notice that a newer version was available. So far so good, until I clicked on UPDATE NOW. Then - NOTHING HAPPENED. I researched to see if I could try another way, and finally found that I could use the Search charm on my PC (Windows 8.1), for "Apple Software Update". But when that brought up the update screen, it wouldn't even let me know one was available. It just gave this error message: "The Apple Software Update server could not be found. Check your Internet settings and try again." But here was the clincher for me - I also have a laptop with same OS & iTunes, that I WAS able to update with the same version of Apple Software Updater 2.2. So I assumed it was NOT an Apple issue as many have complained, since it worked fine on one device, but not the other. So I followed the advice given here by c0ret3x, but first compared those settings he mentioned in the Internet Options/Advanced/Security, and sure enough THAT ONE ITEM was indeed unchecked on that laptop that worked, and was CHECKED on the desktop where it was not working. So, unchecking that feature absolutely allowed iTunes Updating to work properly. THANK YOU, THANK YOU to "c0ret3x" .. !!