Can I use 2 Keyboards and 2 Mice at the same time with one Mac?

Simple. I have a music studio and I would like essentially 2 work stations on the same computer. Mac Pro

Each station will have a Piano style MIDI keyboard....a QWERTY keyboard and a mouse.....if the QWERTY and mice could be bluetooth that would be great. If they have to be wired that would be OK.

I'm trying to avoid a KVM switch or anything like that. Just want to go straight into the Mac and run a program from two work stations at the same time

Thank you for your advice!