Q: Audio ads

There is a video or audio ad running in Safari. Just locate it in order to stop it. Using an adblocker would help prevent more such annoyances. If you can't find it:

Fixes for Adware and Pop-ups

 

1. Malwarebytes
   
2. DetectX 2.11
   
3. Remove adware that displays pop-up ads and graphics on your Mac
   
4. Stop pop-up ads and adware in Safari - Apple Support
    

[Please ignore remarks such as “Don't use any kind of "anti-virus" or "anti-malware" product on a Mac.“ Such remonstrations are an exaggeration. They may be needed in some situations, but need not be installed or used for all circumstances. Furthermore, adware removal programs make the job of removal much easier. They require no permanent installation to remove adware or other types of malware. They do no damage, and they don’t make you more vulnerable to attack.]

You can also install an adblocker in Safari's Extensions.