I posted result from these diagnostic tools, wchich I done last week:
SMART Utility

DriveDx


It seems, that is some problem with HDD - PENDING BAD SECTORS (id 197) - 32 bad sectors. But there was in last week.
Yesterday I tried repair it - I formatted my HDD with secure formating with "7-Pass Erase" option - http://main.makeuseoflimited.netdna-cdn.com/wp-content/uploads/2012/07/secure-er ase.png?323f2c
It took about 24 hours and after that I done tests with same tools as before:

DriveDx


Results from SMART Utility and DriveDx seems better than before. There was 32 bad sectors with id 197 (see my previous reply's attachment) and now there is only 1 bad sector with id 197 (see attachments in this reply).
Do you still think, that my problem with beachballing is in HDD and I should replace it?
When I had problem with beachballing (after install I still have without problem, but still only clean osx without data from backup) it stop play music from iTunes or movies in VLC for a while during beachballing. But what I forgot to mention, that also stop music from youtube or spotify in web browser. Is could be problem with HDD when stop play from browser - not from HDD?
I still thing, that could be problem with RAM memory. I post you report from EtreCheck after fresh instal and formating with "7 pass errase" and fresh install OSX. You see, that I have only 660 MB free RAM. It is too litle for 8GB RAM after fresh install systems without any application.
Please write me your opinion. Thank you very much.
EtreCheck version: 3.0.5 (309)
Report generated 2016-09-25 18:55:29
Download EtreCheck from https://etrecheck.com
Runtime 1:23
Performance: Excellent
Click the [Support] links for help with non-Apple products.
Click the [Details] links for more information about that line.
Problem: Beachballing
Hardware Information: ⓘ
iMac (21.5-inch, Late 2012)
[Technical Specifications] - [User Guide] - [Warranty & Service]
iMac - model: iMac13,1
1 2,7 GHz Intel Core i5 CPU: 4-core
8 GB RAM Upgradeable - [Instructions]
BANK 0/DIMM0
4 GB DDR3 1600 MHz ok
BANK 1/DIMM0
4 GB DDR3 1600 MHz ok
Bluetooth: Good - Handoff/Airdrop2 supported
Wireless: en1: 802.11 a/b/g/n
Video Information:ⓘ
NVIDIA GeForce GT 640M - VRAM: 512 MB
iMac 1920 x 1080
System Software:ⓘ
OS X El Capitan 10.11.6 (15G31) - Time since boot: about 8 hours
Disk Information:ⓘ
APPLE HDD ST1000LM024 disk0 : (1 TB) (Rotational)
EFI (disk0s1) <not mounted> : 210 MB
Macintosh HD (disk0s2) / : 999.35 GB (977.30 GB free)
Recovery HD (disk0s3) <not mounted> [Recovery]: 650 MB
USB Information:ⓘ
Apple Inc. FaceTime HD Camera (Built-in)
Apple Inc. BRCM20702 Hub
Apple Inc. Bluetooth USB Host Controller
Thunderbolt Information:ⓘ
Apple Inc. thunderbolt_bus
Gatekeeper:ⓘ
Mac App Store and identified developers
System Launch Agents:ⓘ
[not loaded] 6 Apple tasks
[loaded] 154 Apple tasks
[running] 78 Apple tasks
System Launch Daemons:ⓘ
[not loaded] 48 Apple tasks
[loaded] 155 Apple tasks
[running] 87 Apple tasks
Launch Daemons:ⓘ
[loaded] com.adobe.fpsaud.plist (2016-08-30) [Support]
User Login Items:ⓘ
iTunesHelper Aplikácia (/Applications/iTunes.app/Contents/MacOS/iTunesHelper.app)
Internet Plug-ins:ⓘ
FlashPlayer-10.6: 23.0.0.162 - SDK 10.9 (2016-09-25) [Support]
QuickTime Plugin: 7.7.3 (2016-07-09)
Flash Player: 23.0.0.162 - SDK 10.9 (2016-09-25) [Support]
Default Browser: 601 - SDK 10.11 (2016-07-09)
3rd Party Preference Panes: ⓘ
Flash Player (2016-08-30) [Support]
Time Machine:ⓘ
Time Machine not configured!
Top Processes by CPU:ⓘ
3% WindowServer
3% fontd
1% Activity Monitor
1% kernel_task
0% coreaudiod
Top Processes by Memory:ⓘ
1.18 GB com.apple.WebKit.WebContent(3)
768 MB kernel_task
459 MB softwareupdated
197 MB system_installd
131 MB mds_stores
Virtual Memory Information:ⓘ
660 MB Free RAM
7.35 GB Used RAM (2.96 GB Cached)
0 B Swap Used
Diagnostics Information:ⓘ
Sep 25, 2016, 10:40:28 AM Self test - passed