Really slow Mac Mini on first start up

I bought my Mac Mini because older PC took an age to start up. Now my Mac Mini is even worse. I also have an old laptop (2010) which I installed Windows 10 on, and it is much faster than my Mac! W10 is up and running on browser/email before Mac even gets to user log in page!

From advice on other posts, I ran EtreCheck and uncovered a printer issue with HP software. Got that sorted and it really helped. But its gone just as bad, ran EtreCheck again, results below, albeit this was when the Mac was still loading up, but done intentionally to see if I can find what's holding it up. There is nothing obvious in this, can anyone see something I'm missing please.

(Conscious there are other posts like this but saw someone getting a telling off for adding their isses to the same post accusing them of "thread-jacking")

EtreCheck version: 3.0.3 (307)

Report generated 2016-09-17 08:11:02

Download EtreCheck from https://etrecheck.com

Runtime 11:48

Performance: Poor

Click the [Support] links for help with non-Apple products.

Click the [Details] links for more information about that line.

Problem: Computer is too slow

Hardware Information: ⓘ

Mac mini (Late 2012)

[Technical Specifications] - [User Guide] - [Warranty & Service]

Mac mini - model: Macmini6,2

1 2.3 GHz Intel Core i7 CPU: 4-core

4 GB RAM Upgradeable - [Instructions]

BANK 0/DIMM0

2 GB DDR3 1600 MHz ok

BANK 1/DIMM0

2 GB DDR3 1600 MHz ok

Bluetooth: Good - Handoff/Airdrop2 supported

Wireless: en1: 802.11 a/b/g/n

Video Information: ⓘ

Intel HD Graphics 4000

S236HL 1920 x 1080

System Software: ⓘ

OS X El Capitan 10.11.6 (15G1004) - Time since boot: less than an hour

Disk Information: ⓘ

APPLE HDD HTS541010A9E662 disk0 : (1 TB) (Rotational)

EFI (disk0s1) <not mounted> : 210 MB

Macintosh HD (disk0s2) / : 999.35 GB (607.22 GB free)

Recovery HD (disk0s3) <not mounted> [Recovery]: 650 MB

USB Information: ⓘ

Apple, Inc. IR Receiver

Apple Inc. BRCM20702 Hub

Apple Inc. Bluetooth USB Host Controller

Thunderbolt Information: ⓘ

Apple Inc. thunderbolt_bus

Gatekeeper: ⓘ

Mac App Store and identified developers

Kernel Extensions: ⓘ

/Library/Application Support/Avast/components/fileshield/unsigned

[loaded] com.avast.AvastFileShield (3.0.0 - SDK 10.9 - 2016-08-18) [Support]

/Library/Application Support/Avast/components/proxy/unsigned

[loaded] com.avast.PacketForwarder (2.1 - SDK 10.11 - 2016-08-18) [Support]

System Launch Agents: ⓘ

[not loaded] 7 Apple tasks

[loaded] 154 Apple tasks

[running] 77 Apple tasks

System Launch Daemons: ⓘ

[failed] com.apple.security.syspolicy.plist (2015-08-23)

[not loaded] 45 Apple tasks

[loaded] 155 Apple tasks

[running] 90 Apple tasks

Launch Agents: ⓘ

[failed] com.adobe.ARMDCHelper.cc24aef4a1b90ed56a725c38014c95072f92651fb65e1bf9c8e43c37a2 3d420d.plist (2016-07-12) [Support]

[running] com.avast.secureline.update-agent.plist (2016-07-04) [Support]

[loaded] com.avast.secureline.userinit.plist (2016-07-04) [Support]

[running] com.avast.update-agent.plist (2016-08-22) [Support]

[loaded] com.avast.userinit.plist (2016-08-22) [Support]

[loaded] com.google.keystone.agent.plist (2016-07-12) [Support]

[loaded] com.oracle.java.Java-Updater.plist (2016-08-23) [Support]

Launch Daemons: ⓘ

[loaded] com.adobe.ARMDC.Communicator.plist (2016-07-12) [Support]

[loaded] com.adobe.ARMDC.SMJobBlessHelper.plist (2016-07-12) [Support]

[loaded] com.adobe.fpsaud.plist (2016-06-29) [Support]

[loaded] com.avast.init.plist (2016-08-22) [Support]

[loaded] com.avast.secureline.init.plist (2016-07-04) [Support]

[loaded] com.avast.secureline.uninstall.plist (2016-07-04) [Support]

[loaded] com.avast.secureline.update.plist (2016-07-04) [Support]

[loaded] com.avast.uninstall.plist (2016-08-22) [Support]

[loaded] com.avast.update.plist (2016-08-22) [Support]

[loaded] com.google.keystone.daemon.plist (2016-09-02) [Support]

[loaded] com.microsoft.office.licensing.helper.plist (2014-02-26) [Support]

[loaded] com.oracle.java.Helper-Tool.plist (2016-08-23) [Support]

User Launch Agents: ⓘ

[failed] com.adobe.ARM.[...].plist (2014-09-02) [Support]

[loaded] com.avast.home.userinit.plist (2016-08-22) [Support]

[loaded] com.avast.secureline.home.userinit.plist (2016-07-05) [Support]

[loaded] com.f-secure.sync.BTCloud.plist (2015-07-31) [Support]

[failed] com.lastpass.LastPassHelper.plist (2015-04-14) [Support]

[running] com.spotify.webhelper.plist (2016-09-11) [Support]

User Login Items: ⓘ

iTunesHelper Application (/Applications/iTunes.app/Contents/MacOS/iTunesHelper.app)

Dropbox Application (/Applications/Dropbox.app)

Internet Plug-ins: ⓘ

FlashPlayer-10.6: 22.0.0.209 - SDK 10.9 (2016-07-19) [Support]

QuickTime Plugin: 7.7.3 (2016-07-22)

AdobePDFViewerNPAPI: 15.017.20053 - SDK 10.11 (2016-08-03) [Support]

AdobePDFViewer: 15.017.20053 - SDK 10.11 (2016-08-03) [Support]

Flash Player: 22.0.0.209 - SDK 10.9 (2016-07-19) Outdated! Update

Default Browser: 601 - SDK 10.11 (2016-07-22)

SharePointBrowserPlugin: 14.6.7 - SDK 10.6 (2016-08-25) [Support]

nplastpass: 3.1.89 - SDK 10.10 (2015-04-14) [Support]

Silverlight: 5.1.41105.0 - SDK 10.6 (2015-12-21) [Support]

JavaAppletPlugin: Java 8 Update 101 build 13 (2016-08-23) Check version

User internet Plug-ins: ⓘ

WebEx64: 1.0 - SDK 10.6 (2015-07-17) [Support]

Google Earth Web Plug-in: 7.1 (2013-10-07) [Support]

Safari Extensions: ⓘ

LastPass - LastPass - https://lastpass.com (2015-09-04)

3rd Party Preference Panes: ⓘ

Flash Player (2016-06-29) [Support]

Java (2016-06-22) [Support]

Time Machine: ⓘ

Time Machine not configured!

Top Processes by CPU: ⓘ

17% update_dyld_shared_cache

8% kernel_task

6% WindowServer

1% systemstatsd

1% com.avast.daemon

Top Processes by Memory: ⓘ

905 MB update_dyld_shared_cache

421 MB kernel_task

152 MB Safari

147 MB Dropbox

127 MB mdworker(10)

Virtual Memory Information: ⓘ

137 MB Free RAM

3.86 GB Used RAM (1.10 GB Cached)

67 MB Swap Used

Diagnostics Information: ⓘ

Sep 17, 2016, 07:50:32 AM Self test - passed