Airplay no longer working in iTunes 12.5.1
I've been using airplay from iTunes on Mac to an Airport Express and to a Bowers & Wilkins Z2 for several years, both seamlessly with no dropouts. After updating iTunes on my Mac to 12.5.1, I get stuttering audio and inconsistent connections. The only thing that has changed in my entire setup is the iTunes update. Connections to both the airport express and Z2 are both wired, not wireless, so I know there is not interference or an issue with wireless networking. Is anyone else experiencing this?
Mac mini, OS X Yosemite (10.10.5)